Stearic acid-N-hydroxysuccinimide ester

Stearic acid-N-hydroxysuccinimide ester - Names and Identifiers

Name	Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS
Synonyms	OCTADECANOIC ACID-NHSE N-SUCCINIMIDYL STEARATE N-(Stearoyloxy)succiniMide STEARIC ACID-N-HYDROXYSUCCINIMIDE ESTER N-HYDROXY SUCCINIMIDO STEARIC ACID ESTER 1-(octadecanoyloxy)pyrrolidine-2,5-dione N-Hydroxy Succinimido Stearic Acid Ester 1-[(1-Oxooctadecyl)oxy]-2,5-pyrrolidinedione 2,5-PYRROLIDINEDIONE, 1-[(1-OXOOCTADECYL)OXY]- stearicacid-n-hydroxysuccinimideesterstearicacid-nhs Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS
CAS	14464-32-5
InChI	InChI=1/C22H39NO4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(26)27-23-20(24)18-19-21(23)25/h2-19H2,1H3

Stearic acid-N-hydroxysuccinimide ester - Physico-chemical Properties

Molecular Formula	C22H39NO4
Molar Mass	381.55
Density	1.01±0.1 g/cm3(Predicted)
Melting Point	92-93°C
Boling Point	473.1±28.0 °C(Predicted)
Flash Point	239.9°C
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly)
Vapor Presure	4.06E-09mmHg at 25°C
Appearance	Solid
Color	White to Off-White
Storage Condition	2-8°C
Refractive Index	1.487

Stearic acid-N-hydroxysuccinimide ester - Risk and Safety

WGK Germany

Stearic acid-N-hydroxysuccinimide ester - Introduction

acid-N-hydroxysuccinimide Stearic acid-NHS(N-hydroxysuccinimide ester of Stearic acid) is an organic compound, which is obtained by esterification of N-hydroxysuccinimide (N-hydroxysuccinimide) with stearic acid (stearic acid). Here is some information about the nature, use, formulation and safety of Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS:

Nature:
Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS is a white or light yellow solid, odorless at room temperature. It has a high melting point and relatively low solubility, and is soluble in organic solvents such as dimethyl sulfoxide (DMSO) and dichloromethane.

Use:
Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS is often used as an activating reagent in the chemical field to change the chemical activity of compounds. It can be coupled with amino acids, peptides, proteins and other molecules for the synthesis of new bioactive molecules, protein covalent modification and drug synthesis.

Method:
Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS is generally obtained by esterification of Stearic acid with N-hydroxysuccinimide. The reaction is usually carried out in an alcoholic solvent such as dichloromethane, ethanol and the like. The reaction conditions can be optimized according to requirements.

Safety Information:
Stearic acid-N-hydroxysuccinimide ester Stearic acid-NHS is relatively stable, but as a chemical, still need to pay attention to safe use. Direct contact with skin and eyes should be avoided. If contact is made, rinse immediately with plenty of water. Pay attention to ventilation during operation and follow the safe operation procedures for chemicals.

Last Update：2024-04-09 02:00:42